welcome to oneEDSvoice
- a positively charged Ehlers Danlos Syndrome community.- join today!
- login
Patients with Ehlers-Danlos Syndrome Type IV Lack Type III Collagen
source: Proceedings of the National Academy of Sciences of the United States of America
year: 1975
authors: Pope FM, Martin GR, Lichtenstein JR, Penttinen R, Gerson B, Rowe DW, McKusick VA
summary/abstract:One of the genetically distinct collagens (type III) normally found in skin, aorta, and intestine is missing from the tissues of patients with the Ehlers-Danlos syndrome type IV. While skin fibroblasts from other individuals synthesize both types I and III collagen. Ehlers-Danlos syndrome IV cells synthesize only type I. These results suggest that the fragile skin, blood vessels, and intestines of Ehlers-Danlos syndrome IV patients result from an absence of type III collagen.
organization: National Institute of Dental Research Bethesda; Johns Hopkins Hospital; Armed Forces Institute of PathologyDOI: 10.1073/pnas.72.4.1314
read more full text source
expertly curated content related to this topic
-
Excessively Redundant Umbilical Skin as a Potential Early Clinical Feature of Morquio Syndrome and FKBP14-related Eh...Several umbilical abnormalities have bee...
-
Central Sensitization as the Mechanism Underlying Pain in Joint Hypermobility Syndrome/Ehlers-Danlos Syndrome, Hyper...BACKGROUND: Patients with joint hypermo...
-
Marco Castori, MD, PhDMarco Castori obtained his PhD degree wi...
-
Neil Schechter, MDDr. Neil Schechter currently directs the...
-
Vascular Ehlers-Danlos Syndrome; Brandi’s Storyhttps://www.youtube.com/watch?v=ZwnVAnN1...
-
Brad T Tinkle, MD PhDPresident & CEO at Dr. Brad T Tinkle...
-
Patrick S. Agnew, DPMDr. Patrick S. Agnew is a Podiatrist (fo...