welcome to oneEDSvoice
- a positively charged Ehlers Danlos Syndrome community.- join today!
- login
Patients with Ehlers Danlos Syndrome and CRPS: A Possible Association?
source: Pain
year: 2006
authors: Stoler JM, Oaklander AL
summary/abstract:Rare patients are left with chronic pain, vasodysregulation, and other symptoms that define complex regional pain syndrome (CRPS), after limb traumas. The predisposing factors are unknown. Genetic factors undoubtedly contribute, but have not yet been identified. We report four CRPS patients also diagnosed with the classical or hypermobility forms of Ehlers Danlos syndrome (EDS), inherited disorders of connective tissue. These patients had been diagnosed using standard diagnostic criteria for CRPS and for EDS. All had sustained joint injury; in three this had been surgically treated. The association of these two diagnoses leads us to hypothesize that EDS might contribute to the development of CRPS in one or more of the following ways: via stretch injury to nerves traversing hypermobile joints, increased fragility of nerve connective tissue, or nerve trauma from more frequent surgery. We review the clinical presentation of the different Ehlers Danlos syndromes and provide clinical criteria that can be used to screen CRPS patients for EDS for clinical or research purposes.
organization: Massachusetts General Hospital, Harvard Medical SchoolDOI: 10.1016/j.pain.2006.02.022
read more full text source
expertly curated content related to this topic
-
The Metropolitan Neurosurgery Group, LLCAll members of the Metropolitan Group ar...
-
Bone Involvement in Adult Patients Affected with Ehlers-Danlos SyndromeThe Ehlers-Danlos syndrome is characteri...
-
Thoracoabdominal Aortic Repair in a Patient with Ehlers-danlos SyndromeType IV Ehlers-Danlos syndrome is a life...
-
Diane O’Leary, PhDDiane O’Leary is an independent resear...
-
Joint Hypermobility Syndrome (Ehlers-Danlos): What Causes The Pain?Are you so flexible you can do tricks? D...
-
Jan Dommerholt, PT, DPT, MPS, DAAPMDr. Jan Dommerholt, PT, DPT, MPS, DAAPM,...
-
Clinical and Molecular Manifestations of Heritable Connective Tissue DisordersThe purposes of this study are to identi...