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Joint Hypermobility–Clinical Aspects

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source: Proceedings of the Royal Society of Medicine

year: 1971

authors: Grahame R


Hippocrates, in the fourth century BC, made the first known reference to hypermobility, when he described the Scythians as being ‘so loose-limbed that they were unable to draw a bow-string or hurl a javelin’. It was only at the end of the 19th century, however, that hypermobility of joints was recognized as being of any clinical significance. I refer to the description by Tschernogobow in Moscow in 1892 of what we now refer to as the Ehlers-Danlos syndrome. He rightly attributed the association of hyperextensibility of the skin and hypermobility and luxation of the joints to ‘a fundamental and generalized inadequacy of connective tissue’. Four years later, Marfan (1896) described the syndrome which now bears his name.

organization: Guy's Hospital

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