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reference materials

Fibromuscular Dysplasia

key information

source: Merck Manual

year: 2014

authors: John W. Hallett


Fibromuscular dysplasia includes a heterogenous group of nonatherosclerotic, noninflammatory arterial changes, causing some degree of vascular stenosis, occlusion, or aneurysm. Fibromuscular dysplasia usually occurs in women aged 40 to 60. The cause is unknown. However, there may be a genetic component, and smoking may be a risk factor. Fibromuscular dysplasia is more common among people with certain connective tissue disorders (eg, Ehlers-Danlos syndrome type 4, cystic medial necrosis, hereditary nephritis, neurofibromatosis).

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