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scientific articles

Ehlers-Danlos Syndrome

key information

source: Proceedings of the Royal Society of Medicine

year: 1939

authors: Weber FP, Huber H


The patient (P. R.) is a young man, aged 21, who has enjoyed good health. Over both shins he has patches of old atrophic (” papyraceous “) scarring resulting from injuries at football, which he ceased playing two years ago. Over the knees he has infiltrated, somewhat purpuric, areas of scarring, especially on the right side, where there are two ulcers. The skin about both elbows is loose ” cutis laxa ” rather than “cutis hyperelastica” and over the left olecranon there is a cherry-sized loose connective-tissue ” pseudo-tumour “. There is a smaller one over the right olecranon.

The small joints of the hands show over-extensibility. He also shows -;so-called” acrocyanosis of the hands without any special tendency to chilblains. There are none of the movable fatty ” spherules ” in the subcutaneous tissue, which have been a conspicuous feature in some other cases

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