welcome to oneEDSvoice
- a positively charged Ehlers Danlos Syndrome community.- join today!
- login
Dermal Ultrastructure in Low Beighton Score Members of 17 Families with Hypermobile-Type Ehlers-Danlos Syndrome
source: Journal of Biomedicine and Biotechnology
year: 2012
authors: Hermanns-Lê T, Reginster MA, Piérard-Franchimont C, Delvenne P, Piérard GE, Manicourt D
summary/abstract:The distinction between the Ehlers-Danlos syndrome hypermobile type (EDSH) and the benign joint hypermobility syndrome (BJHS) is unclear. The aim of the present study was to compare skin ultrastructural abnormalities of EDSH and BJHS among different families. Skin of 23 EDSH, 27 BJHS, and 41 asymptomatic subjects from 17 families was examined using transmission electron microscopy. Similar ultrastructural abnormalities were found irrespective of the Beighton score. Flower-like collagen fibrils represented the key change and elastic fibers were altered as well. Beighton score is a clinical parameter rating joint mobility that appeared unrelated to quantitative and qualitative collagen ultrastructural alterations in the skin. Some EDSH family members fit with BJHS diagnosis. BJHS possibly represents a mild variant of EDSH.
organization: University Hospital Sart TilmanDOI: 10.1155/2012/878107
read more full text source
expertly curated content related to this topic
-
Mast Cells & Collagen Behaving BadlyThanks for visiting my Blog. I'm not a...
-
Ehlers-Danlos Syndrome Type VIII: Periodontitis, Easy Bruising, Marfanoid Habitus, and Distinctive FaciesAn 11-year-old boy had a history of easy...
-
Positional Magnetic Resonance Imaging for People with Ehlers-Danlos Syndrome or Suspected Craniovertebral or Cervica...Given the current absence of evidence fo...
-
Dr Tim JenkinsonDr Tim Jenkinson has been a consultant i...
-
EDS-H & JHSUnderstanding Ehlers-Danlos Syndrome Hyp...
-
Ann Rodiger, M.AmSATAnn Rodiger is the Founder and Director...